Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28274692 | 0.80 | TSHR (0.50) | SMN1; SMN2TSHRMTORALDH1A1HPGD | |
| SCHEMBL28845523 | 0.80 | TSHR (0.46) | SMN1; SMN2TSHRMTORALDH1A1HPGD | |
| SCHEMBL9489728 | 0.79 | COMT (0.50) | TSHRALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL31634213 | 0.79 | COMT (0.50) | TSHRALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL8563296 | 0.75 | ALDH1A1 (0.51) | SMN1; SMN2TSHRALDH1A1HPGDKDM4E | |
| SCHEMBL10728701 | 0.74 | ALDH1A1 (0.50) | SMN1; SMN2TSHRALDH1A1HPGDKDM4E | |
| SCHEMBL2767017 | 0.72 | ALDH1A1 (0.56) | SMN1; SMN2TSHRALDH1A1HPGDKDM4E | |
| SCHEMBL25084127 | 0.71 | TRPV4 (0.50) | ALDH1A1KDM4EMAPTLMNANPSR1 | |
| SCHEMBL31028698 | 0.71 | CA2 (0.56) | ALDH1A1HPGDKDM4ELMNAHTT | |
| SCHEMBL3666996 | 0.71 | CA2 (0.56) | ALDH1A1HPGDKDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106831551-B | A kind of method that ionic liquid method synthesizes the halogenated -3- substituted hydrocarbon radical sulfonyl pyridine of 2- and its intermediate | 山东师范大学 | 2019-09-24 | — | — | CN | disclosed |
| CN-106748988-B | A kind of method that supercritical ultrasonics technology synthesizes the halogenated -3- substituted hydrocarbon radical sulfonyl pyridine of 2- and its intermediate | 山东师范大学 | 2019-05-28 | — | — | CN | disclosed |
| CN-106866514-B | A kind of method that Aqueous phase synthesizes the halogenated -3- substituted hydrocarbon radical sulfonyl pyridine of 2- and its intermediate | 山东师范大学 | 2019-05-28 | — | — | CN | disclosed |
| CN-106866515-B | A kind of sulfonyl pyridine derivative and its synthetic method | 山东师范大学 | 2019-05-28 | — | — | CN | disclosed |
| CN-106518757-B | A kind of method that microwave method synthesizes the halogenated -3- substituted hydrocarbon radical sulfonyl pyridine of 2- and its intermediate | 山东师范大学 | 2019-03-19 | — | — | CN | disclosed |