Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | CFD | P00746 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22668308 | 0.81 | LOXL2 (0.60) | LOXL2ENPP2HTR2CCFDPNMT | |
| SCHEMBL28293176 | 0.80 | CES2 (0.55) | LOXL2ENPP2HTR2CCFDPNMT | |
| SCHEMBL27594322 | 0.77 | LOXL2 (0.65) | LOXL2ENPP2HTR2CCFDPNMT | |
| SCHEMBL31500915 | 0.76 | FOLH1 (0.66) | LOXL2ENPP2ANPEPENPEPFOLH1 | |
| SCHEMBL509423 | 0.76 | LOXL2 (0.66) | LOXL2ENPP2CFDFOLH1TSHR | |
| SCHEMBL31500919 | 0.76 | FOLH1 (0.66) | LOXL2ENPP2ANPEPENPEPFOLH1 | |
| SCHEMBL61226 | 0.76 | FOLH1 (0.66) | LOXL2ENPP2ANPEPENPEPFOLH1 | |
| SCHEMBL29364575 | 0.76 | LOXL2 (0.66) | LOXL2ENPP2CFDFOLH1TSHR | |
| SCHEMBL28879968 | 0.75 | LOXL2 (0.57) | LOXL2ENPP2HTR2CCFDPNMT | |
| SCHEMBL2642751 | 0.74 | LOXL2 (0.66) | LOXL2ENPP2CFDMRGPRX4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104995176-B | Hydantoins that modulate BACE mediated APP processing | 巴克老龄化研究所 | 2019-02-22 | — | — | CN | disclosed |