Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.55 |
| ▸ | CES1 | P23141 | 3/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | CFD | P00746 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | F9 | P00740 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | PGK2 | P07205 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28275646 | 0.80 | LOXL2 (0.54) | CES2CES1LOXL2ENPP2CFD | |
| SCHEMBL22668308 | 0.78 | LOXL2 (0.60) | LOXL2ENPP2CFDHTR2CANPEP | |
| SCHEMBL11215252 | 0.77 | CES2 (0.62) | CES2CES1LMNATSHR | |
| SCHEMBL11215254 | 0.77 | CES2 (0.62) | CES2CES1LMNAFOLH1TSHR | |
| SCHEMBL19859915 | 0.77 | LMNA (0.67) | CES2CES1LOXL2LMNACYP1A2 | |
| SCHEMBL19859914 | 0.77 | CES2 (0.67) | CES2CES1LOXL2LMNACFD | |
| SCHEMBL27594322 | 0.75 | LOXL2 (0.65) | LOXL2ENPP2CFDHTR2CPNMT | |
| SCHEMBL21700186 | 0.75 | ENPP2 (0.54) | LOXL2ENPP2ADRA1DPNMTPGK1 | |
| SCHEMBL6533707 | 0.75 | ENPP2 (0.54) | LOXL2ENPP2ADRA1DPNMTPGK1 | |
| SCHEMBL28291616 | 0.74 | CES2 (0.53) | CES2CES1LOXL2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109665953-A | A method of preparing styrax class compound | 盐城锦明药业有限公司 | 2019-04-23 | — | — | CN | disclosed |