Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | DBH | P09172 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | CFD | P00746 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 4/20 | 0.42 |
| ▸ | NOS2 | P35228 | 4/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10277237 | 0.84 | BCL2 (0.47) | LOXL2KDM4EDBHGAARECQL | |
| SCHEMBL14519856 | 0.82 | GAA (0.46) | LOXL2KDM4EDBHGAARECQL | |
| SCHEMBL10019208 | 0.82 | FOLH1 (0.46) | KDM4EDBHGAARECQLSLC7A5 | |
| SCHEMBL15761203 | 0.82 | GAA (0.46) | LOXL2KDM4EDBHGAARECQL | |
| SCHEMBL10819620 | 0.81 | LOXL2 (0.55) | LOXL2KDM4EDBHGAARECQL | |
| SCHEMBL20330179 | 0.81 | ITGA4 (0.51) | LOXL2KDM4EDBHGAARECQL | |
| SCHEMBL28275646 | 0.81 | LOXL2 (0.54) | LOXL2ENPP2CFDNOS1NOS2 | |
| SCHEMBL7945435 | 0.80 | GAA (0.59) | KDM4EDBHGAARECQLALDH1A1 | |
| SCHEMBL2642751 | 0.79 | LOXL2 (0.66) | LOXL2ENPP2CFDNOS1NOS2 | |
| SCHEMBL24138282 | 0.79 | GAA (0.43) | LOXL2KDM4EDBHGAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023099669-A1 | PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR | ZEALAND PHARMA A/S (DK) | 2023-06-08 | — | — | WO | disclosed |
| US-11046695-B2 | Fragment synthesis of substituted cyclic peptides | ZEALAND PHARMA A/S (DK) | 2021-06-29 | — | — | US | disclosed |
| US-20200361944-A1 | FRAGMENT SYNTHESIS OF CYCLIC PEPTIDES | ZEALAND PHARMA A/S (DK) | 2020-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11046695-B2 | Fragment synthesis of substituted cyclic peptides | VIP, NPPA, NGLY1 | LOXL2 3424/4885KDM4E 4730/4885DBH 1649/4885 |
| US-20200361944-A1 | FRAGMENT SYNTHESIS OF CYCLIC PEPTIDES | VIP, NPPA, NGLY1 | LOXL2 3809/4885KDM4E 4748/4885DBH 1839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.