Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.55 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.53 |
| ▸ | TNF | P01375 | 2/20 | 0.52 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.52 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.51 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13065792 | 0.95 | FFAR1 (0.64) | FFAR1L3MBTL1FFAR4REV1TNF | |
| SCHEMBL2827594 | 0.87 | L3MBTL1 (0.52) | FFAR1L3MBTL1REV1TNFNOD2 | |
| SCHEMBL21172122 | 0.87 | FFAR1 (0.68) | FFAR1FFAR4HRH3RXRARXRB | |
| SCHEMBL19266404 | 0.86 | FFAR1 (0.61) | FFAR1L3MBTL1FFAR4PRMT5WDR77 | |
| SCHEMBL21171655 | 0.84 | FFAR1 (0.61) | FFAR1L3MBTL1FFAR4REV1HRH3 | |
| Trifluoroacetic Acid SCHEMBL2827678 | 0.80 | FFAR1 (0.53) | FFAR1FFAR4HRH3RXRARXRB | |
| SCHEMBL28449037 | 0.80 | FFAR1 (0.60) | FFAR1L3MBTL1REV1TNFNOD2 | |
| Trifluoroacetic Acid SCHEMBL2828355 | 0.80 | FFAR1 (0.50) | FFAR1FFAR4HRH3RXRARXRB | |
| SCHEMBL19266392 | 0.80 | REV1 (0.61) | FFAR1L3MBTL1REV1TNFNOD2 | |
| Trifluoroacetic Acid SCHEMBL2827690 | 0.79 | FFAR1 (0.54) | FFAR1FFAR4HRH3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1731505-B1 | ALKOXYPHENYLPROPANOIC ACID DERIVATIVES | TAKEDA PHARMACEUTICAL (JP) | 2015-01-14 | — | — | EP | disclosed |
| EP-2253315-A1 | Alkoxyphenylpropanoic acid derivatives | Takeda Pharmaceutical Company Limited (JP) | 2010-11-24 | — | — | EP | disclosed |
| US-7517910-B2 | Alkoxyphenylpropanoic acid derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-14 | — | — | US | disclosed |
| US-20070213364-A1 | Alkoxyphenylpropanoic Acid Derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-09-13 | — | — | US | disclosed |
| EP-1731505-A1 | ALKOXYPHENYLPROPANOIC ACID DERIVATIVES | Takeda Pharmaceutical Company Limited (JP) | 2006-12-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213364-A1 | Alkoxyphenylpropanoic Acid Derivatives | GPR119, FFAR1, GPR55 | FFAR1 2/4885L3MBTL1 3748/4885FFAR4 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.