Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10164810 | 0.85 | CASP1 (0.44) | CASP1MEN1TTRALBKMT2A | |
| SCHEMBL25255223 | 0.85 | MEN1 (0.47) | MEN1TTRALBKMT2ACXCR1 | |
| SCHEMBL23674669 | 0.83 | XDH (0.49) | MEN1TTRALBKMT2ACXCR1 | |
| SCHEMBL17109321 | 0.81 | MEN1 (0.44) | MEN1TTRALBKMT2ACXCR1 | |
| SCHEMBL7450183 | 0.81 | MEN1 (0.44) | MEN1TTRALBKMT2ACXCR1 | |
| SCHEMBL5045602 | 0.79 | XDH (0.49) | CASP1PARP2PARP15PARP10PARP1 | |
| SCHEMBL24022839 | 0.78 | CASP1 (0.44) | CASP1TTRALBPARP2PARP15 | |
| SCHEMBL3176877 | 0.78 | DGAT1 (0.55) | CASP1MEN1KMT2APARP2PARP15 | |
| SCHEMBL4896547 | 0.78 | CASP1 (0.51) | CASP1KMT2APARP2PARP15PARP10 | |
| SCHEMBL2965097 | 0.78 | PARP15 (0.46) | CASP1PARP2PARP15PARP10PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109293585-A | A method of halobenzamides rapid synthesis quinazolinones are utilized under microwave condition in water phase | 云南师范大学 | 2019-02-01 | — | — | CN | disclosed |