Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 4/20 | 0.38 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25255223 | 0.85 | MEN1 (0.47) | MEN1KMT2ATTRALBCXCR1 | |
| SCHEMBL23674669 | 0.83 | XDH (0.49) | MEN1KMT2ATTRALBCXCR1 | |
| SCHEMBL17109321 | 0.81 | MEN1 (0.44) | MEN1KMT2ATTRALBCXCR1 | |
| SCHEMBL28276264 | 0.81 | CASP1 (0.44) | MEN1KMT2ATTRALBCXCR1 | |
| SCHEMBL27839112 | 0.81 | RAB9A (0.42) | MEN1KMT2ATTRALBCXCR1 | |
| SCHEMBL4778338 | 0.81 | CA12 (0.42) | MEN1KMT2ATTRALBCXCR1 | |
| SCHEMBL8757233 | 0.79 | SMN1; SMN2 (0.41) | MEN1KMT2AALDH1A1MAPTXDH | |
| SCHEMBL4259236 | 0.79 | ALDH1A1 (0.50) | CXCR1CXCR2ALDH1A1MAPTXDH | |
| SCHEMBL3361866 | 0.79 | LRRK2 (0.48) | MEN1KMT2AALDH1A1MAPTGSK3B | |
| SCHEMBL14393261 | 0.78 | MEN1 (0.35) | MEN1KMT2ATTRALBCXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300353-B1 | FOR THERAPY OF FUNGAL INFECTIONS | BASILEA PHARMACEUTICA AG, A SWISS COMPANY (CH) | 2001-10-09 | — | — | US | disclosed |
| US-5958950-A | CARDIOVASCULAR DISORDERS | WARNER-LAMBERT COMPANY (US) | 1999-09-28 | — | — | US | disclosed |
| WO-1999045008-A1 | 3-[4-(4-CYANOPHENYL)THIAZOL-2-Y)]-1-(1H-1,2,4-TRIAZOL-1-YL)-BUTAN-2-OL DERIVATIVES HAVING ANTIFUNGAL ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 1999-09-10 | — | — | WO | disclosed |
| WO-1997012615-A1 | BENZIMIDAZOLE DERIVATIVES AS 15-LO INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1997-04-10 | — | — | WO | disclosed |