Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11964042 | 0.84 | SPHK1 (0.45) | SPHK1ALDH1A1MAPTPKMHPGD | |
| SCHEMBL27831899 | 0.76 | CYP2C19 (0.43) | SPHK1ALDH1A1MAPTPKMHPGD | |
| SCHEMBL2828593 | 0.75 | GAA (0.42) | ALDH1A1MAPTHPGDALOX15CYP2C19 | |
| SCHEMBL13479740 | 0.73 | CYP2C19 (0.55) | ALDH1A1MAPTPKMHPGDHSD17B10 | |
| SCHEMBL2827279 | 0.73 | CASP3 (0.44) | ALDH1A1MAPTHPGDCYP2C19LMNA | |
| SCHEMBL22716072 | 0.71 | CYP2C19 (0.49) | ALDH1A1MAPTPKMHPGDHSD17B10 | |
| SCHEMBL22715137 | 0.71 | CYP2C19 (0.53) | ALDH1A1MAPTPKMHPGDHSD17B10 | |
| SCHEMBL15306510 | 0.70 | KMT2A (0.38) | SPHK1ALDH1A1MAPTPKMHPGD | |
| SCHEMBL12892550 | 0.70 | ALDH1A1 (0.54) | ALDH1A1HPGDCYP2C19LMNAKMT2A | |
| SCHEMBL10848836 | 0.68 | ALDH1A1 (0.50) | ALDH1A1MAPTPKMHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828258-B1 | N-SUBSTITUTED IMIDES AS POLYMERIZATION INITIATORS | BASF SE (DE) | 2010-06-30 | — | — | EP | disclosed |
| US-7723399-B2 | N-substituted imides as polymerization initiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| US-7723399-B2 | N-substituted imides as polymerization initiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| US-7723399-B2 | N-substituted imides as polymerization initiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| US-20080132600-A1 | N-Substituted Imides As Polymerization Initiators | CIBA SPECIALTY CHEMICALS CORP. | 2008-06-05 | — | — | US | disclosed |
| US-20080132600-A1 | N-Substituted Imides As Polymerization Initiators | CIBA SPECIALTY CHEMICALS CORP. | 2008-06-05 | — | — | US | disclosed |
| US-20080132600-A1 | N-Substituted Imides As Polymerization Initiators | CIBA SPECIALTY CHEMICALS CORP. | 2008-06-05 | — | — | US | disclosed |
| CN-101056893-A | N-substituted imides as polymerization initiators | CIBA SC HOLDING AG (CH) | 2007-10-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132600-A1 | N-Substituted Imides As Polymerization Initiators | NR1H3, SIGMAR1, NR1H2 | SPHK1 1929/4885ALDH1A1 2799/4885MAPT 4750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.