SCHEMBL282769

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL328194	0.93	NOS3 (0.49)	CHRM1CHRM5CHRM3DRD2HTR2A
	SCHEMBL10127991	0.91	DRD2 (0.52)	CHRM1CHRM5CHRM3DRD2HTR2A
	SCHEMBL328234	0.88	EGFR (0.54)	CHRM1CHRM5CHRM3DRD2HTR2A
	SCHEMBL498915	0.83	NOS3 (0.56)	CHRM1CHRM5CHRM3DRD2HTR2A
	SCHEMBL328304	0.82	CHRM1 (0.50)	CHRM1CHRM5CHRM3DRD2HTR2A
	SCHEMBL10127945	0.81	NOS3 (0.48)	CHRM1CHRM5CHRM3KCNH2EGFR
	SCHEMBL13071332	0.81	CHRM1 (0.43)	CHRM1CHRM5CHRM3DRD2HTR2A
	SCHEMBL16522709	0.81	CHRM1 (0.47)	CHRM1CHRM5CHRM3NOS3NOS1
	SCHEMBL16897923	0.80	POLB (0.57)	DRD2HTR2AMCHR1
	SCHEMBL10128002	0.79	EGFR (0.54)	CHRM1DRD2HTR2AMCHR1EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.