SCHEMBL328194

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL282769	0.93	CHRM1 (0.53)	NOS3NOS1NOS2DRD4CHRM1
	SCHEMBL498915	0.90	NOS3 (0.56)	NOS3NOS1NOS2DRD4CHRM1
	SCHEMBL10127945	0.89	NOS3 (0.48)	NOS3NOS1NOS2DRD4CHRM1
	SCHEMBL10127991	0.83	DRD2 (0.52)	DRD4CHRM1CHRM5CHRM3DRD2
	SCHEMBL328234	0.83	EGFR (0.54)	CHRM1CHRM5CHRM3DRD2HTR2A
	SCHEMBL16522709	0.83	CHRM1 (0.47)	NOS3NOS1NOS2CHRM1CHRM5
	SCHEMBL282824	0.81	ALDH1A1 (0.51)	NOS3NOS1NOS2DRD4CHRM1
	SCHEMBL18226834	0.80	CHRM1 (0.42)	NOS3NOS1NOS2DRD4CHRM1
	SCHEMBL8127407	0.80	ATAD2 (0.56)	NOS3NOS1CHRM1CHRM5CHRM3
	SCHEMBL216988	0.80	NOS3 (0.56)	NOS3NOS1NOS2CHRM1CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.