Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28255640 | 0.79 | HTT (0.38) | TYK2PNMT | |
| SCHEMBL27645613 | 0.77 | RXRB (0.50) | RXRB | |
| SCHEMBL16648351 | 0.77 | DRD2 (0.37) | DRD2DRD3HTR6PLAU | |
| Hydrochloric Acid SCHEMBL4715513 | 0.75 | DRD2 (0.36) | DRD2DRD3HTR6ITGB3ITGA2B | |
| SCHEMBL28869247 | 0.74 | NTRK2 (0.45) | DRD2TYK2 | |
| SCHEMBL19675178 | 0.73 | DRD2 (0.41) | DRD2DRD3HTR6PNMT | |
| Hydrochloric Acid SCHEMBL4716276 | 0.72 | DRD2 (0.37) | DRD2DRD3HTR6ITGB3ITGA2B | |
| SCHEMBL20672086 | 0.72 | DRD2 (0.35) | DRD2DRD3HTR6PLAU | |
| SCHEMBL28835938 | 0.72 | SMN1; SMN2 (0.40) | DRD2 | |
| SCHEMBL28071113 | 0.72 | DRD2 (0.49) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104045552-B | Medicinal compound as neuroprotective agent | 江苏先声药业有限公司 | 2019-06-11 | — | — | CN | disclosed |
| CN-109265443-A | Heterocyclic compound and its application as ASK inhibitor | 南京圣和药业股份有限公司 | 2019-01-25 | — | — | CN | disclosed |