SCHEMBL28277385

SCHEMBL28277385

Brc1cc(Br)cc(-c2ccc3c(c2-c2cc(Br)cc(Br)c2)Cc2ccccc2-3)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.40
PNMT P11086 1/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
EGFR P00533 1/20 0.35
SRD5A2 P31213 1/20 0.35
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA4 P22748 2/20 0.34
CA6 P23280 2/20 0.34
CYP1A2 P05177 3/20 0.33
HTR2B P41595 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3553779 0.85 PNMT (0.46) PGRPNMTNPC1RAB9AKDM4E
SCHEMBL28276610 0.83 CRHBP (0.42) PGRPNMTNPC1RAB9AKDM4E
SCHEMBL27983232 0.82 PGR (0.40) PGRPNMTNPC1RAB9AKDM4E
SCHEMBL150217 0.78 ADORA2A (0.47) PGRPNMTNPC1RAB9AKDM4E
SCHEMBL29766669 0.78 ADORA2A (0.47) PGRPNMTNPC1RAB9AKDM4E
SCHEMBL31030083 0.77 PGR (0.43) PGRPNMTNPC1RAB9AKDM4E
SCHEMBL9473016 0.77 PNMT (0.40) PGRPNMTNPC1RAB9AKDM4E
SCHEMBL28222407 0.77 PNMT (0.40) PGRPNMTNPC1RAB9AKDM4E
SCHEMBL28224970 0.77 PGR (0.43) PGRPNMTNPC1RAB9AKDM4E
SCHEMBL28291449 0.77 PGR (0.43) PGRPNMTNPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105906546-B Fluorine derivative for organic electroluminescence device 默克专利有限公司 2019-02-22 CN disclosed