Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 3/20 | 0.39 |
| ▸ | FPR2 | P25090 | 2/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28277464 | 0.94 | KMT2A (0.38) | EPHX2SCN1ASCN2ASCN3ACHRNA7 | |
| SCHEMBL28328550 | 0.92 | EPHX2 (0.46) | EPHX2SCN1ASCN2ASCN3ACHRNA7 | |
| SCHEMBL27911300 | 0.88 | CHRM3 (0.49) | EPHX2ACACBCHRM3CHRM2 | |
| SCHEMBL27721841 | 0.88 | CHRM3 (0.49) | EPHX2ACACBCHRM3CHRM2 | |
| SCHEMBL27874081 | 0.88 | CHRM3 (0.49) | EPHX2ACACBCHRM3CHRM2 | |
| SCHEMBL28126238 | 0.80 | CYP2D6 (0.55) | SCN1ASCN2ASCN3A | |
| SCHEMBL27638895 | 0.80 | EPHX2 (0.46) | EPHX2GPR119ACACBFPR2PROKR1 | |
| SCHEMBL27989232 | 0.78 | LIPG (0.47) | EPHX2ACACBGRIN1GRIN2B | |
| SCHEMBL20179924 | 0.77 | GPR119 (0.58) | GPR119 | |
| SCHEMBL28014736 | 0.77 | FAAH (0.42) | EPHX2GPR119ACACBCHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096274-A | It can be used for treating the aryl-linking compound of human tumor, neurology and amynologic disease | 比奥根MA公司 | 2018-12-28 | — | — | CN | disclosed |
| CN-108947913-A | It can be used for treating the aryl-linking compound of human tumor, neurology and amynologic disease | 比奥根MA公司 | 2018-12-07 | — | — | CN | disclosed |
| CN-106459002-B | Biaryl compounds useful in the treatment of human oncological, neurological and immunological diseases | 比奥根MA公司 | 2018-08-21 | — | — | CN | disclosed |