SCHEMBL28277995

SCHEMBL28277995

CCCOC(=O)C(OC(=O)c1ccc(CC)cc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.56
POLB P06746 2/20 0.56
LMNA P02545 2/20 0.53
MAPT P10636 4/20 0.48
KMT2A Q03164 4/20 0.48
MEN1 O00255 3/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 1/20 0.48
NPSR1 Q6W5P4 3/20 0.45
MAPK1 P28482 1/20 0.45
UBE2N P61088 1/20 0.45
ESR1 P03372 2/20 0.44
CHRM1 P11229 1/20 0.44
TSHR P16473 1/20 0.44
SLC6A2 P23975 1/20 0.44
KDR P35968 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
THRB P10828 1/20 0.42
HPGD P15428 1/20 0.42
ESR2 Q92731 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28549109 0.92 ALDH1A1 (0.54) ALDH1A1POLBLMNAMAPTKMT2A
SCHEMBL28548556 0.92 LMNA (0.50) ALDH1A1POLBLMNAMAPTKMT2A
SCHEMBL28277999 0.92 LMNA (0.63) ALDH1A1POLBLMNAMAPTKMT2A
SCHEMBL28551059 0.91 ALDH1A1 (0.53) ALDH1A1POLBLMNAMAPTKMT2A
SCHEMBL28279403 0.90 LMNA (0.48) ALDH1A1POLBLMNAMAPTKMT2A
SCHEMBL28554575 0.89 NPSR1 (0.57) ALDH1A1POLBLMNAMAPTKMT2A
SCHEMBL28543648 0.89 ALDH1A1 (0.61) ALDH1A1POLBLMNAMAPTKMT2A
SCHEMBL28539168 0.88 LMNA (0.51) ALDH1A1POLBLMNAMAPTKMT2A
SCHEMBL28554580 0.88 LMNA (0.51) ALDH1A1POLBLMNAMAPTKMT2A
SCHEMBL28278027 0.85 NPC1 (0.47) ALDH1A1POLBLMNAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109553705-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553712-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN claimed
CN-109553712-A A kind of catalytic component and its catalyst for olefinic polymerization 中国石油化工股份有限公司 2019-04-02 CN claimed
CN-109553705-A A kind of catalytic component and preparation method thereof for olefinic polymerization 中国石油化工股份有限公司 2019-04-02 CN claimed
CN-109553705-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553712-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN disclosed