Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28311729 | 0.86 | SMN1; SMN2 (0.43) | TDP1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Tert-Butyl Formate SCHEMBL28278580 | 0.85 | SIGMAR1 (0.44) | TDP1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Tert-Butyl Formate SCHEMBL27718748 | 0.83 | TDP1 (0.42) | L3MBTL1TDP1ALDH1A1MEN1KMT2A | |
| Tert-Butyl Formate SCHEMBL27721169 | 0.83 | TDP1 (0.42) | TDP1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1900720 | 0.82 | L3MBTL1 (0.63) | L3MBTL1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Tert-Butyl Formate SCHEMBL28088768 | 0.82 | TDP1 (0.41) | L3MBTL1TDP1ALDH1A1MEN1KMT2A | |
| Tert-Butyl Formate SCHEMBL27998227 | 0.81 | TDP1 (0.43) | TDP1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Tert-Butyl Formate SCHEMBL27601010 | 0.81 | ALDH1A1 (0.41) | TDP1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8742997 | 0.81 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Tert-Butyl Formate SCHEMBL28313688 | 0.80 | TDP1 (0.42) | TDP1ALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311880-A | For treating and preventing hepatitis b virus infected new tetrahydropyridine miazines compound | 豪夫迈·罗氏有限公司 | 2019-02-05 | — | — | CN | disclosed |