Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.40 |
| ▸ | GCGR | P47871 | 3/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.40 |
| ▸ | TNKS | O95271 | 2/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27985279 | 0.89 | MAPK1 (0.40) | ALDH1A1TP53MGAMGAASI | |
| SCHEMBL6647087 | 0.83 | NISCH (0.48) | GAASMN1; SMN2NPC1RAB9ATNKS | |
| SCHEMBL13680573 | 0.80 | MAPK1 (0.54) | ALDH1A1MGAMGAASIMGAM2 | |
| SCHEMBL10554989 | 0.80 | GAA (0.44) | ALDH1A1TP53MGAMGAASI | |
| SCHEMBL3635215 | 0.80 | NPC1 (0.44) | ALDH1A1TP53GAASMN1; SMN2KDM4E | |
| SCHEMBL797826 | 0.80 | TNKS (0.40) | ALDH1A1GAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL28277777 | 0.79 | MGAM (0.53) | MGAMGAASIMGAM2SMN1; SMN2 | |
| SCHEMBL49612 | 0.79 | GAA (0.52) | ALDH1A1GAASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL28329121 | 0.78 | GAA (0.47) | ALDH1A1GAASMN1; SMN2KDM4ENPC1 | |
| Phosphine SCHEMBL28142196 | 0.78 | GAA (0.50) | ALDH1A1GAASMN1; SMN2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311902-B | Substituted imidazo [1,2-b ] pyridazines, imidazo [1,5-b ] pyridazines, related compounds, and uses thereof | BIAL研发投资股份有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-109311902-A | Substituted imidazo [1,2-b] pyridazine, substituted imidazo [1,5-b] pyridazine, related compound and their purposes in treatment medical disorder | 溶酶体治疗股份有限公司 | 2019-02-05 | — | — | CN | disclosed |