SCHEMBL13680573

SCHEMBL13680573

Cc1c[nH]c(-c2ccc(Cl)cc2)n1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.54
KDM4E B2RXH2 2/20 0.44
MGAM O43451 1/20 0.44
GAA P10253 1/20 0.44
SI P14410 1/20 0.44
MGAM2 Q2M2H8 1/20 0.44
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
ALPL P05186 1/20 0.43
DCUN1D1 Q96GG9 1/20 0.42
TNKS O95271 1/20 0.40
TNKS2 Q9H2K2 1/20 0.40
PARP2 Q9UGN5 1/20 0.40
NR1H2 P55055 1/20 0.40
NR1H3 Q13133 1/20 0.40
MAPT P10636 2/20 0.38
MAPK13 O15264 2/20 0.38
GCGR P47871 2/20 0.38
MAPK12 P53778 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27985279 0.89 MAPK1 (0.40) MAPK1MGAMGAASIMGAM2
SCHEMBL6647087 0.83 NISCH (0.48) MAPK1GAANPC1RAB9ASMN1; SMN2
SCHEMBL28279252 0.80 ALDH1A1 (0.46) KDM4EMGAMGAASIMGAM2
SCHEMBL3635215 0.80 NPC1 (0.44) MAPK1KDM4EGAANPC1RAB9A
SCHEMBL797826 0.80 TNKS (0.40) MAPK1GAANPC1RAB9ASMN1; SMN2
SCHEMBL10554989 0.80 GAA (0.44) MGAMGAASIMGAM2NPC1
SCHEMBL29346840 0.79 NPC1 (0.47) MAPK1KDM4ENPC1RAB9AALDH1A1
SCHEMBL49612 0.79 GAA (0.52) KDM4EGAANPC1RAB9ASMN1; SMN2
SCHEMBL29843542 0.79 ERCC1 (0.43) MAPK1
SCHEMBL28856158 0.79 ERCC1 (0.43) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111922553-A Copper surface protective agent for advanced wafer packaging field and preparation method thereof 深圳市创智成功科技有限公司 2020-11-13 CN claimed
CN-107971655-B High-heat-resistance organic solder flux and application thereof 永星化工(上海)有限公司 2019-12-27 CN claimed
CN-111922553-A Copper surface protective agent for advanced wafer packaging field and preparation method thereof 深圳市创智成功科技有限公司 2020-11-13 CN disclosed
CN-107971655-B High-heat-resistance organic solder flux and application thereof 永星化工(上海)有限公司 2019-12-27 CN disclosed
US-20170334912-A1 Purine Diones As Wnt Pathway Modulators AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-11-23 US disclosed
US-7582658-B2 Bicyclic compound ASAHI KASEI PHARMA CORPORATION (JP) 2009-09-01 US disclosed
US-7582658-B2 Bicyclic compound ASAHI KASEI PHARMA CORPORATION (JP) 2009-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170334912-A1 Purine Diones As Wnt Pathway Modulators WNT1, WNT3A, CTNNB1 MAPK1 920/4885KDM4E 3779/4885MGAM 4162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.