Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ABL2 | P42684 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26317184 | 0.98 | TDP1 (0.51) | TDP1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1143736 | 0.91 | TDP1 (0.61) | TDP1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7191275 | 0.82 | ALDH1A1 (0.57) | TDP1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1143598 | 0.81 | ALDH1A1 (0.51) | TDP1MAPTALDH1A1KDM4EHTT | |
| SCHEMBL31464210 | 0.81 | ALDH1A1 (0.51) | TDP1MAPTALDH1A1KDM4EHTT | |
| SCHEMBL28075403 | 0.81 | TDP1 (0.70) | TDP1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26317191 | 0.80 | GPR17 (0.44) | TDP1MAPTNPC1RAB9ASMN1; SMN2 | |
| Formaldehyde SCHEMBL9220828 | 0.79 | TDP1 (0.68) | TDP1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19146 | 0.79 | TDP1 (0.73) | TDP1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7981247 | 0.79 | TDP1 (0.73) | TDP1MAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109453814-A | Containing sulfonic group and the polymer supported rhodium catalyst of Phosphine ligands multi-stage porous and preparation and application | 中国科学院大连化学物理研究所 | 2019-03-12 | — | — | CN | claimed |
| CN-109453814-A | Containing sulfonic group and the polymer supported rhodium catalyst of Phosphine ligands multi-stage porous and preparation and application | 中国科学院大连化学物理研究所 | 2019-03-12 | — | — | CN | disclosed |