4-Nitroaniline

4-Nitroaniline

SCHEMBL6705231

CSCC[C@H](N)C(=O)O.Nc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 4/20 0.49
GRM4 Q14833 4/20 0.49
GRM6 O15303 1/20 0.49
ALDH1A1 P00352 1/20 0.49
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
MAPT P10636 1/20 0.45
ESR1 P03372 2/20 0.44
CYP19A1 P11511 2/20 0.44
ESR2 Q92731 2/20 0.44
FNTA P49354 2/20 0.43
FNTB P49356 2/20 0.43
GRIK1 P39086 1/20 0.43
GRIK2 Q13002 1/20 0.43
PKM P14618 1/20 0.42
KMO O15229 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Nitroaniline SCHEMBL10381907 1.00 GRM8 (0.49) GRM8GRM4GRM6ALDH1A1KMT2A
4-Nitroaniline SCHEMBL9278097 0.93 GRM8 (0.44) GRM8GRM4GRM6ALDH1A1KMT2A
Glutamic Acid SCHEMBL3126271 0.82 GRM8 (0.53) GRM8GRM4GRM6ALDH1A1KMT2A
Glutamic Acid SCHEMBL29088693 0.81 GRM8 (0.51) GRM8GRM4GRM6ALDH1A1KMT2A
Lysine SCHEMBL28385610 0.80 GSR (0.56) GRM8GRM4GRM6ALDH1A1KMT2A
Lysine SCHEMBL28327845 0.80 GSR (0.56) GRM8GRM4GRM6ALDH1A1KMT2A
Sulfanilamide SCHEMBL28279686 0.80 CA2 (0.56)
Methionine SCHEMBL9990641 0.79 BHMT (0.47) GRM8GRM4GRM6GRIK1GRIK2
Racemethionine SCHEMBL9990635 0.79 BHMT (0.47) GRM8GRM4GRM6GRIK1GRIK2
2-Nitroaniline SCHEMBL22394594 0.79 GRM8 (0.46) GRM8GRM4GRM6ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109576337-B Kit for detecting mycoplasma genitalium 郑州安图生物工程股份有限公司 2022-04-08 CN disclosed
CN-113163799-A Corn protein hydrolysate and preparation method thereof 嘉吉公司 2021-07-23 CN disclosed
CN-110887933-A Enzyme activity determination method based on real-time absorbance determination in constant-temperature catalytic reaction process 中国科学院天津工业生物技术研究所 2020-03-17 CN disclosed
US-20040077031-A1 Novel methionine aminopeptidase-2 and uses thereof ABBOTT LABORATORIES 2004-04-22 US disclosed
WO-2002005804-A1 COMPOUNDS AND METHODS SMITHKLINE BEECHAM CORPORATION (US) 2002-01-24 WO disclosed
EP-0375841-A1 Isolation, purification, and characterization of the aminopeptidases: AP1 and AP122 THE GENERAL HOSPITAL CORPORATION (US) 1990-07-04 EP disclosed
WO-1990002815-A1 ISOLATION, PURIFICATION, AND CHARACTERIZATION OF THE AMINOPEPTIDASES: MAS II AND MAS III THE GENERAL HOSPITAL CORPORATION (US) 1990-03-22 WO disclosed
WO-1990002813-A1 ISOLATION, PURIFICATION, AND CHARACTERIZATION OF THE AMINOPEPTIDASES: AP1 AND AP122 THE GENERAL HOSPITAL CORPORATION (US) 1990-03-22 WO disclosed
WO-1990002814-A1 ISOLATION, PURIFICATION, AND CHARACTERIZATION OF THE AMINOPEPTIDASES: AP2, API, AND APX THE GENERAL HOSPITAL CORPORATION (US) 1990-03-22 WO disclosed
EP-0359163-A2 Isolation, purification, and characterization of the aminopeptidases: mas II and III THE GENERAL HOSPITAL CORPORATION (US) 1990-03-21 EP disclosed
EP-0359164-A2 Isolation, purification, and characterization of the aminopeptidases: AP2, API, and APX THE GENERAL HOSPITAL CORPORATION (US) 1990-03-21 EP disclosed