Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.56 |
| ▸ | CA1 | P00915 | 9/20 | 0.56 |
| ▸ | CA12 | O43570 | 5/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Toluenesulfonamide SCHEMBL6645679 | 1.00 | CA2 (0.56) | CA2CA1CA12CA9CA3 | |
| P-Toluenesulfonamide SCHEMBL6642628 | 0.99 | CA2 (0.55) | CA2CA1CA12CA9CA3 | |
| P-Toluenesulfonamide SCHEMBL6642631 | 0.99 | CA2 (0.55) | CA2CA1CA12CA9CA3 | |
| Racemethionine SCHEMBL29260976 | 0.89 | KIF11 (0.46) | CA2CA1KIF11KDM4EPOLB | |
| Methionine SCHEMBL30298013 | 0.89 | KIF11 (0.46) | CA2CA1KIF11KDM4EPOLB | |
| Sulfanilamide SCHEMBL28279686 | 0.89 | CA2 (0.56) | CA2CA1CA12CA9CA6 | |
| Methionine SCHEMBL15688811 | 0.88 | KIF11 (0.45) | CA2CA1KIF11KDM4EPOLB | |
| Racemethionine SCHEMBL18351662 | 0.88 | KIF11 (0.45) | CA2CA1KIF11KDM4EPOLB | |
| Methionine SCHEMBL1236853 | 0.88 | KIF11 (0.45) | CA2CA1KIF11KDM4EPOLB | |
| Racemethionine SCHEMBL1236856 | 0.88 | KIF11 (0.45) | CA2CA1KIF11KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986384-A4 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2004-09-15 | — | — | EP | claimed |
| EP-0986384-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 2000-03-22 | — | — | EP | claimed |