Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | PARP1 | P09874 | 16/20 | 0.61 |
| ▸ | PARP10 | Q53GL7 | 12/20 | 0.61 |
| ▸ | PARP15 | Q460N3 | 7/20 | 0.61 |
| ▸ | PARP14 | Q460N5 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850002 | 0.86 | MEN1 (0.67) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL4893340 | 0.85 | PARP1 (0.66) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL5425792 | 0.85 | MEN1 (0.65) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL895009 | 0.83 | PARP1 (0.63) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL408480 | 0.83 | PARP1 (0.63) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL4531507 | 0.83 | ALDH1A1 (0.71) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL895690 | 0.83 | MEN1 (0.63) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL29761319 | 0.83 | PARP1 (0.63) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL9921486 | 0.82 | MEN1 (0.61) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL18671651 | 0.81 | KMT2A (0.87) | MEN1KMT2APARP1PARP10PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108138177-B | The combination of Dbait molecule and PARP inhibitor is used for the purposes for the treatment of cancer | 法国居里学院 | 2019-03-19 | — | — | CN | disclosed |