SCHEMBL408480

SCHEMBL408480

NC(=O)C(=O)Nc1cccc(C(N)=O)c1

nearest known ligand 0.63

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 15/20 0.63
MEN1 O00255 1/20 0.63
KMT2A Q03164 1/20 0.63
PARP10 Q53GL7 12/20 0.59
PARP15 Q460N3 7/20 0.59
PARP14 Q460N5 4/20 0.59
TDP1 Q9NUW8 1/20 0.53
GPR35 Q9HC97 1/20 0.50
ALDH1A1 P00352 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2850002 0.85 MEN1 (0.67) PARP1MEN1KMT2APARP10PARP15
SCHEMBL4893340 0.83 PARP1 (0.66) PARP1MEN1KMT2APARP10PARP15
SCHEMBL28280295 0.83 MEN1 (0.65) PARP1MEN1KMT2APARP10PARP15
SCHEMBL5425792 0.83 MEN1 (0.65) PARP1MEN1KMT2APARP10PARP15
SCHEMBL30716170 0.83 PARP1 (0.57) PARP1MEN1KMT2APARP10PARP15
SCHEMBL895690 0.81 MEN1 (0.63) PARP1MEN1KMT2APARP10PARP15
SCHEMBL29761319 0.81 PARP1 (0.63) PARP1MEN1KMT2APARP10PARP15
SCHEMBL4531507 0.81 ALDH1A1 (0.71) PARP1MEN1KMT2APARP10PARP15
SCHEMBL895009 0.81 PARP1 (0.63) PARP1MEN1KMT2APARP10PARP15
SCHEMBL9921486 0.80 MEN1 (0.61) PARP1MEN1KMT2APARP10PARP15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104736148-B Parazoon expeling composition and the expelling method of parazoon 三井化学AGRO株式会社 2018-01-12 CN claimed
CN-104736148-A Composition for animal parasite extermination and method for animal parasite extermination MITSUI CHEMICALS AGRO INC 2015-06-24 CN claimed
CN-108640871-B Fluorine-containing pyridine piperazine urea compound and application thereof 青岛科技大学 2020-03-20 CN disclosed
CN-104736148-B Parazoon expeling composition and the expelling method of parazoon 三井化学AGRO株式会社 2018-01-12 CN disclosed
WO-2016143650-A1 3-AMINOOXALYLAMINOBENZAMIDE COMPOUND AND USE FOR CONTROLLING HARMFUL ARTHROPOD 住友化学株式会社 2016-09-15 WO disclosed
WO-2016143652-A1 3-AMINOOXALYLAMINOBENZAMIDE COMPOUND AND USE FOR CONTROLLING HARMFUL ARTHROPOD 住友化学株式会社 2016-09-15 WO disclosed
CN-104736148-A Composition for animal parasite extermination and method for animal parasite extermination MITSUI CHEMICALS AGRO INC 2015-06-24 CN disclosed
US-8541473-B2 3-aminoxalyl-aminobenzamide derivatives and insecticidal and miticidal agents containing same as active ingredient AGRO-KANESHO CO., LTD. (JP) 2013-09-24 US disclosed
WO-2012164698-A1 3-AMINOOXALYLAMINOBENZAMIDE DERIVATIVE, AND INSECTICIDAL OR MITICIDAL AGENT COMPRISING SAME AS ACTIVE INGREDIENT アグロカネショウ株式会社 (JP) 2012-12-06 WO disclosed
WO-2012077221-A1 3-AMINOOXALYLAMINOBENZAMIDE DERIVATIVE, AND INSECTICIDAL AND ACARICIDAL AGENT CONTAINING SAME AS ACTIVE INGREDIENT アグロカネショウ株式会社 (JP) 2012-06-14 WO disclosed
WO-2012042608-A1 3-AMINOBENZOIC ACID DERIVATIVE AND METHOD FOR PRODUCING SAME アグロカネショウ株式会社 (JP) 2012-04-05 WO disclosed
US-20120022263-A1 3-AMINOXALYL-AMINOBENZAMIDE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENT AGRO-KANESHO CO., LTD. (JP) 2012-01-26 US disclosed
EP-2394986-A1 3-AMINOXALYLAMINOBENZAMIDE DERIVATIVES, AND INSECTICIDAL AND MITICIDAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENT Agro-Kanesho Co., Ltd. (JP) 2011-12-14 EP disclosed
WO-2010089881-A1 3-AMINOOXALYLAMINOBENZAMIDE DERIVATIVE AND PESTICIDE/MITICIDE CONTAINING THE DERIVATIVE AS ACTIVE INGREDIENT アグロカネショウ株式会社 (JP) 2010-08-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120022263-A1 3-AMINOXALYL-AMINOBENZAMIDE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENT HDHD5, CBR3, BAK1 PARP1 2095/4885MEN1 1004/4885KMT2A 227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.