Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 11/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718637 | 0.82 | PTGS1 (0.49) | PTGS1MAPK14PTGS2PRKCZ | |
| SCHEMBL6920647 | 0.80 | PTGS1 (0.39) | PTGS1PRKCZMAPT | |
| SCHEMBL16048484 | 0.80 | NOTUM (0.40) | PTGS1PTGS2PRKCZMAPT | |
| SCHEMBL3988930 | 0.80 | PTGS2 (0.44) | PTGS1PTGS2MAPT | |
| SCHEMBL5107107 | 0.79 | BCAT2 (0.48) | PTGS1PTGS2 | |
| SCHEMBL27691526 | 0.76 | PTGS1 (0.53) | PTGS1 | |
| SCHEMBL10843937 | 0.72 | MAPK14 (0.79) | PTGS1MAPK14PTGS2 | |
| SCHEMBL1475136 | 0.72 | — | — | |
| SCHEMBL7323658 | 0.71 | MAPK14 (0.50) | PTGS1MAPK14PTGS2 | |
| SCHEMBL695291 | 0.71 | PTGS1 (0.51) | PTGS1MAPK14PTGS2PRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109336874-B | Preparation method of canagliflozin | 江苏工程职业技术学院 | 2022-03-11 | — | — | CN | disclosed |
| CN-109336874-A | A kind of preparation method of canagliflozin | 江苏工程职业技术学院 | 2019-02-15 | — | — | CN | disclosed |