Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28280396 | 0.80 | PTGS1 (0.59) | PTGS2PTGS1MAPT | |
| SCHEMBL16048484 | 0.80 | NOTUM (0.40) | PTGS2PTGS1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6920647 | 0.80 | PTGS1 (0.39) | PTGS1ALDH1A1MAPTMAPK1NPC1 | |
| SCHEMBL5107107 | 0.79 | BCAT2 (0.48) | PTGS2PTGS1ALDH1A1TSHRMAPK1 | |
| SCHEMBL8089263 | 0.74 | PTGS2 (0.49) | PTGS2PTGS1ALDH1A1MAPTTSHR | |
| SCHEMBL28228496 | 0.72 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL956381 | 0.72 | — | — | |
| Ammonia Solution, Strong SCHEMBL23908216 | 0.71 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL2231313 | 0.71 | ALDH1A1 (0.47) | PTGS2PTGS1ALDH1A1MAPTTSHR | |
| SCHEMBL2781156 | 0.71 | PTGS2 (0.46) | PTGS2ALDH1A1MAPTTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112934203-A | Heavy metal removing material and method for removing heavy metal in Chinese herbal medicine extract | 苏州大学 | 2021-06-11 | — | — | CN | disclosed |
| EP-2064193-A1 | HETEROCYCLIC GPR40 MODULATORS | Amgen, Inc (US) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008030520-A1 | HETEROCYCLIC GPR40 MODULATORS | AMGEN INC. (US) | 2008-03-13 | — | — | WO | disclosed |