Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.64 |
| ▸ | MC4R | P32245 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820679 | 0.89 | CYP2D6 (0.60) | CYP2D6MC4ROPRM1OPRK1OPRL1 | |
| SCHEMBL96003 | 0.88 | CYP2D6 (0.76) | CYP2D6MC4ROPRM1OPRK1OPRL1 | |
| SCHEMBL8445058 | 0.83 | CYP2D6 (0.62) | CYP2D6MC4ROPRM1OPRK1OPRL1 | |
| SCHEMBL3330332 | 0.80 | OPRM1 (0.52) | CYP2D6OPRM1OPRK1OPRL1OPRD1 | |
| SCHEMBL7264542 | 0.79 | CYP2D6 (1.00) | CYP2D6MC4ROPRM1OPRK1OPRL1 | |
| SCHEMBL16226061 | 0.79 | CYP2D6 (1.00) | CYP2D6MC4ROPRM1OPRK1OPRL1 | |
| SCHEMBL6706135 | 0.79 | CYP2D6 (1.00) | CYP2D6MC4ROPRM1OPRK1OPRL1 | |
| SCHEMBL23850144 | 0.75 | CYP2D6 (0.83) | CYP2D6MC4ROPRM1OPRK1OPRL1 | |
| SCHEMBL8983562 | 0.75 | CYP2D6 (0.83) | CYP2D6MC4ROPRM1OPRK1OPRL1 | |
| SCHEMBL3914022 | 0.75 | CYP2D6 (0.68) | CYP2D6MC4ROPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109526219-A | Benzsulfamide and its purposes as therapeutic agent | 泽农医药公司 | 2019-03-26 | — | — | CN | claimed |
| CN-109526219-A | Benzsulfamide and its purposes as therapeutic agent | 泽农医药公司 | 2019-03-26 | — | — | CN | disclosed |