Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4742342 | 0.86 | KDM4E (0.63) | KDM4ELMNATP53L3MBTL1TAS1R3 | |
| SCHEMBL30269796 | 0.86 | KDM4E (0.63) | KDM4ELMNATP53L3MBTL1TAS1R3 | |
| SCHEMBL42002 | 0.83 | KDM4E (0.78) | KDM4ELMNATP53L3MBTL1ALDH1A1 | |
| SCHEMBL29580772 | 0.83 | KDM4E (0.78) | KDM4ELMNATP53L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL16115604 | 0.82 | KDM4E (0.76) | KDM4ELMNATP53L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9036642 | 0.82 | KDM4E (0.76) | KDM4ELMNATP53L3MBTL1ALDH1A1 | |
| SCHEMBL24196938 | 0.82 | ALOX15 (0.58) | KDM4ELMNAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL26213279 | 0.82 | XDH (0.56) | KDM4ELMNAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL7169528 | 0.81 | KDM4E (0.61) | KDM4ELMNATP53L3MBTL1ALDH1A1 | |
| SCHEMBL30269785 | 0.80 | KDM4E (1.00) | KDM4ELMNATP53L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115843271-A | Indole derivatives and their use for the treatment of cancer | 克洛德贝纳尔-里昂第一大学 | 2023-03-24 | — | — | CN | claimed |
| CN-115843271-B | Indole derivatives and their use for the treatment of cancer | 克洛德贝纳尔-里昂第一大学 | 2024-08-13 | — | — | CN | disclosed |
| CN-115843271-A | Indole derivatives and their use for the treatment of cancer | 克洛德贝纳尔-里昂第一大学 | 2023-03-24 | — | — | CN | disclosed |
| CN-104870422-B | Amine derivative or its salt | 富士胶片富山化学株式会社 | 2019-03-15 | — | — | CN | disclosed |