Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | PRKCG | P05129 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28359769 | 0.78 | CA12 (0.39) | HTTALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL28199752 | 0.76 | BCAT2 (0.43) | HTTALDH1A1HPGDBCL2L1HSD17B10 | |
| SCHEMBL11191248 | 0.75 | HTT (0.39) | HTTALDH1A1HPGDBCL2L1HSD17B10 | |
| SCHEMBL28199201 | 0.74 | HNF4A (0.40) | ALDH1A1HPGDBCL2L1HSD17B10CASP3 | |
| SCHEMBL28280696 | 0.73 | PDCD1 (0.42) | ALDH1A1HPGDBCL2L1HSD17B10 | |
| SCHEMBL28514275 | 0.72 | CES2 (0.42) | ALDH1A1HPGDCES2CES1LMNA | |
| SCHEMBL28199177 | 0.72 | MAPT (0.38) | HTTFOLH1 | |
| SCHEMBL28347361 | 0.71 | SLC6A4 (0.45) | HTT | |
| SCHEMBL1927711 | 0.70 | FOLH1 (0.53) | HTTALDH1A1CES2CES1LMNA | |
| SCHEMBL28869522 | 0.70 | HNF4A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422689-A | A kind of 6- replaces the synthetic method of phenanthridines class compound | 浙江工业大学 | 2019-03-05 | — | — | CN | disclosed |