Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.41 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.41 |
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | MELK | Q14680 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29308758 | 0.91 | CYP11B1 (0.46) | TDP2ALDH1A1MAPK1ADCY8ADCY1 | |
| SCHEMBL20320243 | 0.88 | TDP2 (0.39) | TDP2ALDH1A1MAPK1ADCY8ADCY1 | |
| SCHEMBL16639373 | 0.87 | TDP2 (0.38) | TDP2ALDH1A1MAPK1ADCY8ADCY1 | |
| SCHEMBL21615922 | 0.84 | CYP11B1 (0.39) | TDP2ALDH1A1ADCY8ADCY1ASIC3 | |
| SCHEMBL18214053 | 0.84 | RARB (0.38) | TDP2MAPK1ADCY8ADCY1CYP11B1 | |
| SCHEMBL12619936 | 0.80 | TDP2 (0.53) | TDP2ALDH1A1ASIC3CYP11B1CYP11B2 | |
| SCHEMBL13594 | 0.79 | — | — | |
| SCHEMBL18560276 | 0.79 | TDP1 (0.44) | TDP2ADCY8ADCY1ASIC3PNMT | |
| SCHEMBL6253369 | 0.78 | HSD17B3 (0.51) | TDP2ALDH1A1MAPK1CYP11B1CYP11B2 | |
| Ammonia Solution, Strong SCHEMBL8701960 | 0.77 | PNMT (0.56) | TDP2ASIC3PNMTCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109516923-A | Compounds and organic luminescent device comprising it | 东进世美肯株式会社 | 2019-03-26 | — | — | CN | disclosed |