Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 3/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | LYN | P07948 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1512152 | 0.91 | BCAT2 (0.59) | BCAT2PARP1KDRFLT3MAP4K4 | |
| SCHEMBL3791160 | 0.86 | BCAT2 (0.53) | BCAT2PARP1ABL1KDRFLT3 | |
| SCHEMBL6004326 | 0.84 | BCAT2 (0.71) | BCAT2PARP1KDM4EUSP2ALDH1A1 | |
| SCHEMBL3433069 | 0.84 | BCAT2 (0.71) | BCAT2PARP1KDM4EALDH1A1HPGD | |
| SCHEMBL6131504 | 0.83 | TLR8 (0.48) | BCAT2PARP1ABL1KDRFLT3 | |
| SCHEMBL6590788 | 0.83 | IKBKB (0.52) | BCAT2PARP1MAP4K4FGFR1SRC | |
| SCHEMBL31419622 | 0.81 | BCAT2 (0.49) | BCAT2PARP1KDRKDM4EUSP2 | |
| SCHEMBL7143118 | 0.79 | CHUK (0.61) | BCAT2PARP1DYRK3ROCK2MAP4K4 | |
| SCHEMBL6318211 | 0.79 | NPC1 (0.44) | KDRFLT3KITKDM4EALDH1A1 | |
| SCHEMBL30903677 | 0.79 | IKBKB (0.64) | BCAT2IKBKBCHUKIKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608407-B | Synthetic method of dibenzo seven-membered nitrogen-containing heterocyclic compound | 河北科技大学 | 2020-08-11 | — | — | CN | disclosed |
| CN-109608407-A | A kind of synthetic method of seven member heterocyclic ring containing nitrogen compound of dibenzo | 河北科技大学 | 2019-04-12 | — | — | CN | disclosed |