SCHEMBL28282975

SCHEMBL28282975

CCNc1c(C#N)cccc1-c1ccc(-c2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.42
ADORA1 P30542 5/20 0.42
ADORA2A P29274 4/20 0.42
ADORA2B P29275 1/20 0.39
PPARG P37231 2/20 0.38
GRIA2 P42262 1/20 0.38
GRIA4 P48058 1/20 0.38
KDM4E B2RXH2 4/20 0.37
HPGD P15428 3/20 0.37
TSHR P16473 3/20 0.37
HSD17B10 Q99714 3/20 0.37
ALDH1A1 P00352 3/20 0.36
GAA P10253 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
GALR3 O60755 1/20 0.36
ALOX15 P16050 1/20 0.36
ALOX12 P18054 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4266239 0.79 CYP11B1 (0.36) ADORA1ADORA2AADORA2BKDM4EHPGD
SCHEMBL5338888 0.78 PRKCQ (0.50) ADORA1ADORA2AADORA2BCYP1A2CYP2C9
Hydrochloric Acid SCHEMBL27701462 0.74 TSHR (0.47) ADORA1ADORA2AKDM4EHPGDTSHR
SCHEMBL2016996 0.74 ESR2 (0.70) ESR2GRIA2GRIA4KDM4EHPGD
SCHEMBL27346612 0.73 KCNH2 (0.34) ADORA1ADORA2AKDM4EHPGDTSHR
SCHEMBL23609409 0.72 ALDH1A1 (0.50) ADORA1ADORA2AKDM4EHPGDHSD17B10
SCHEMBL29468705 0.72 DYRK1A (0.38) ADORA1ADORA2AKDM4EHPGDTSHR
SCHEMBL6278704 0.72 ESR2 (0.44) ESR2GRIA2GRIA4KDM4EHPGD
SCHEMBL28315214 0.72 DYRK1A (0.38) ADORA1ADORA2AKDM4EHPGDTSHR
Hydrochloric Acid SCHEMBL6985442 0.72 ESR2 (0.67) ESR2GRIA2GRIA4KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109504166-A A kind of cigarette-brand solidified by ultraviolet ray radiation pearly-lustre gold ink and preparation method thereof 惠州市立美特环保油墨有限公司 2019-03-22 CN disclosed