Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28285367 | 0.84 | SMN1; SMN2 (0.36) | SMN1; SMN2 | |
| SCHEMBL1431164 | 0.82 | SMN1; SMN2 (0.40) | SMN1; SMN2HCAR3FPR2OPRD1OPRK1 | |
| SCHEMBL30554004 | 0.81 | KDM4E (0.42) | SMN1; SMN2FPR2KDM4EOPRD1OPRK1 | |
| SCHEMBL28416467 | 0.79 | FPR2 (0.43) | SMN1; SMN2HCAR3FPR2KDM4E | |
| SCHEMBL28415000 | 0.78 | FPR2 (0.48) | SMN1; SMN2L3MBTL1FPR2KDM4EOPRD1 | |
| SCHEMBL28935871 | 0.76 | KDM4C (0.46) | SMN1; SMN2KDM4EOPRD1OPRK1 | |
| SCHEMBL28381059 | 0.76 | MC4R (0.34) | SMN1; SMN2HCAR3L3MBTL1ADORA2AADORA2B | |
| SCHEMBL28182708 | 0.74 | PTGS2 (0.34) | SMN1; SMN2 | |
| SCHEMBL28705125 | 0.73 | ALDH1A1 (0.51) | KDM4EOPRD1OPRK1 | |
| SCHEMBL23458277 | 0.73 | CYP26A1 (0.32) | SMN1; SMN2HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111187218-B | Application of 1-substituted-1H-imidazole-2-carboxylic acid compound in preparation of metal beta-lactamase inhibitor | 四川大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-111253317-B | 1-substituted-1H-imidazole-2-carboxylic acid compound | 四川大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-111253317-A | 1-substituted-1H-imidazole-2-carboxylic acid compound | 四川大学 | 2020-06-09 | — | — | CN | disclosed |
| CN-111187218-A | Application of 1-substituted-1H-imidazole-2-carboxylic acid compounds in preparation of metal β -lactamase inhibitor | 四川大学 | 2020-05-22 | — | — | CN | disclosed |
| CN-109563050-A | Amide salt compound, for the catalyst of polyurethane production and the production method of polyurethane resin | 广荣化学工业株式会社 | 2019-04-02 | — | — | CN | disclosed |