Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1431164 | 0.80 | SMN1; SMN2 (0.40) | SMN1; SMN2 | |
| SCHEMBL28416467 | 0.77 | FPR2 (0.43) | SMN1; SMN2 | |
| SCHEMBL28283770 | 0.74 | SMN1; SMN2 (0.40) | SMN1; SMN2 | |
| SCHEMBL11335494 | 0.74 | CYP19A1 (0.40) | — | |
| SCHEMBL28706183 | 0.73 | LMNA (0.44) | — | |
| SCHEMBL28705125 | 0.72 | ALDH1A1 (0.51) | — | |
| SCHEMBL27510365 | 0.70 | — | — | |
| SCHEMBL28415000 | 0.70 | FPR2 (0.48) | SMN1; SMN2RAB9A | |
| SCHEMBL28285367 | 0.70 | SMN1; SMN2 (0.36) | SMN1; SMN2 | |
| SCHEMBL29224442 | 0.69 | SMN1; SMN2 (0.39) | SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107250128-A | Cyclic amine derivatives and its medical usage | 东丽株式会社 | 2017-10-13 | — | — | CN | disclosed |