Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RBP4 | P02753 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | IDH2 | P48735 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | ULK1 | O75385 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28284287 | 1.00 | GAA (0.37) | GAARBP4CYP11B2CYP11B1SLC6A2 | |
| SCHEMBL28282655 | 0.94 | GAA (0.41) | GAARBP4CYP11B2CYP11B1SLC6A2 | |
| SCHEMBL28284248 | 0.80 | GAA (0.35) | GAARBP4CYP11B2CYP11B1SLC6A2 | |
| SCHEMBL12029013 | 0.79 | RPS6KA3 (0.39) | SCDSCD5ALDH1A1 | |
| SCHEMBL29435625 | 0.79 | RPS6KA3 (0.39) | SCDSCD5ALDH1A1 | |
| SCHEMBL6155126 | 0.77 | TRPM8 (0.34) | RBP4CYP11B2SCDSCD5ALDH1A1 | |
| SCHEMBL28870641 | 0.77 | ROCK2 (0.33) | — | |
| SCHEMBL28870639 | 0.77 | ROCK2 (0.33) | — | |
| SCHEMBL24988696 | 0.76 | ALDH1A1 (0.35) | GAARBP4CYP11B2SCDSCD5 | |
| SCHEMBL26272326 | 0.76 | ALDH1A1 (0.35) | GAARBP4CYP11B2SCDSCD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415358-A | 6-aminopyridin-3-ylthiazoles as ROR gamma t modulators | 詹森药业有限公司 | 2019-03-01 | — | — | CN | disclosed |