Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.49 |
| ▸ | POLQ | O75417 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28285217 | 0.90 | RORC (0.49) | RORCPOLQMRGPRX4PPARGDDR1 | |
| SCHEMBL28302148 | 0.83 | RORC (0.49) | RORCPOLQMRGPRX4PPARGKDM4C | |
| SCHEMBL28285110 | 0.82 | RORC (0.55) | RORCPOLQMRGPRX4PPARGKDM4C | |
| SCHEMBL19360574 | 0.82 | RORC (0.65) | RORCPOLQMRGPRX4PPARG | |
| SCHEMBL22238330 | 0.80 | RORC (0.51) | RORCPOLQMRGPRX4PPARGKDM4C | |
| SCHEMBL29465610 | 0.80 | RORC (0.64) | RORCPOLQMRGPRX4PPARGPLA2G4A | |
| SCHEMBL19360545 | 0.80 | RORC (0.64) | RORCPOLQMRGPRX4PPARGPLA2G4A | |
| SCHEMBL19360314 | 0.79 | RORC (0.65) | RORCPOLQMRGPRX4PPARG | |
| SCHEMBL22238305 | 0.79 | RORC (0.51) | RORCPOLQMRGPRX4PPARGKDM4C | |
| SCHEMBL28283533 | 0.79 | RORC (0.51) | RORCPOLQMRGPRX4PPARGCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109485595-A | Indole carboxamides analog derivative, preparation method and its application in medicine that hydrophilic radical replaces | 江苏恒瑞医药股份有限公司 | 2019-03-19 | — | — | CN | disclosed |