Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28617698 | 0.96 | HTT (0.47) | KDM4EALDH1A1TSHRTDP1HTT | |
| SCHEMBL7530972 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1MAPTGAAMEN1 | |
| SCHEMBL11029210 | 0.84 | KDM4E (0.44) | KDM4EALDH1A1TSHRTDP1HTT | |
| SCHEMBL8901392 | 0.81 | GAA (0.49) | KDM4EALDH1A1TSHRHTTMAPT | |
| SCHEMBL27391515 | 0.81 | ALDH1A1 (0.57) | KDM4EALDH1A1TSHRHTTMAPT | |
| SCHEMBL28783724 | 0.80 | KDM4E (0.45) | KDM4EALDH1A1HTTMAPTMAPK1 | |
| Potassium Ion SCHEMBL9318787 | 0.80 | ALDH1A1 (0.37) | KDM4EALDH1A1TSHRTDP1HTT | |
| SCHEMBL13696659 | 0.77 | ALDH1A1 (0.51) | KDM4EALDH1A1TDP1HTTMAPT | |
| SCHEMBL28389628 | 0.76 | MAOB (0.49) | KDM4EALDH1A1TSHRHTTMAPT | |
| SCHEMBL1758614 | 0.76 | ALDH1A1 (0.56) | KDM4EALDH1A1TSHRHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109456216-A | A kind of no catalyst is reacted without aromatic amine under the conditions of promotor with the amine that turns of amide derivatives | 湘潭大学 | 2019-03-12 | — | — | CN | disclosed |