Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | HPGD | P15428 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2343599 | 0.84 | HTT (0.62) | GAAKDM4EHTTKMT2AALDH1A1 | |
| SCHEMBL13088443 | 0.83 | ALDH1A1 (0.41) | GAAKDM4EHTTKMT2AALDH1A1 | |
| SCHEMBL27391515 | 0.83 | ALDH1A1 (0.57) | GAAKDM4EHTTKMT2AALDH1A1 | |
| SCHEMBL8901237 | 0.82 | GAA (0.51) | GAAKDM4EHTTKMT2AALDH1A1 | |
| SCHEMBL28285145 | 0.81 | KDM4E (0.48) | GAAKDM4EHTTKMT2AALDH1A1 | |
| SCHEMBL28617698 | 0.81 | HTT (0.47) | GAAKDM4EHTTKMT2AALDH1A1 | |
| SCHEMBL7466908 | 0.79 | KDM4E (0.68) | GAAKDM4EHTTKMT2AALDH1A1 | |
| SCHEMBL6582728 | 0.79 | KDM4E (0.67) | GAAKDM4EHTTKMT2AALDH1A1 | |
| SCHEMBL23468922 | 0.77 | EGFR (0.51) | GAAKDM4EHTTKMT2AALDH1A1 | |
| SCHEMBL156940 | 0.77 | MAPT (0.55) | KDM4EHTTKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686482-A | DOPAMINE RECEPTOR ANTAGONIST | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0757985-A1 | N-(3-PYRROLIDINYL)BENZAMIDE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |