Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28389628 | 0.85 | MAOB (0.49) | KDM4EMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL19415662 | 0.84 | PRKDC (0.43) | KDM4EMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL28285145 | 0.84 | KDM4E (0.48) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL28617698 | 0.84 | HTT (0.47) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL13696659 | 0.82 | ALDH1A1 (0.51) | KDM4EMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL27582567 | 0.77 | KMT2A (0.60) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL1758548 | 0.76 | KMT2A (0.57) | KDM4EMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL7530694 | 0.76 | HTT (0.50) | KDM4EMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL8901392 | 0.75 | GAA (0.49) | KDM4EMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL7530969 | 0.74 | ALDH1A1 (0.51) | KDM4EMAPTALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189891-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-03-27 | — | — | EP | claimed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | claimed |
| WO-2001000594-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-01-04 | — | — | WO | claimed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | disclosed |
| US-4140860-A | BACTERICIDES | STERLING DRUG INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4119668-A | ANTIBACTERIAL AGENTS | STERLING DRUG INC. (US) | 1978-10-10 | — | — | US | disclosed |
| US-4085144-A | ANTIBACTERIAL | STERLING DRUG INC. (US) | 1978-04-18 | — | — | US | disclosed |
| US-4022833-A | ANTIBACTERIAL AGENTS | STERLING DRUG INC. (US) | 1977-05-10 | — | — | US | disclosed |