Fluoranthene

Fluoranthene

SCHEMBL28285154

c1ccc2c(c1)-c1cccc3cccc-2c13.c1ccc2c(c1)[nH]c1ccccc12

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.62
HSD17B10 Q99714 6/20 0.62
MAPK1 P28482 4/20 0.62
TSHR P16473 3/20 0.62
ATM Q13315 3/20 0.62
L3MBTL1 Q9Y468 2/20 0.62
GPR3 P46089 2/20 0.58
HPGD P15428 5/20 0.50
CASP1 P29466 3/20 0.50
CASP7 P55210 2/20 0.50
HIF1A Q16665 2/20 0.50
CYP3A4 P08684 1/20 0.50
PABPC1 P11940 1/20 0.50
DNMT1 P26358 1/20 0.50
TP53 P04637 1/20 0.50
AHR P35869 1/20 0.50
KIF11 P52732 3/20 0.47
IMPDH2 P12268 1/20 0.47
IMPDH1 P20839 1/20 0.47
BCHE P06276 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21302944 0.89 AHR (0.55) ALDH1A1HSD17B10MAPK1TSHRATM
Fluoranthene SCHEMBL28873730 0.88 AHR (0.55) ALDH1A1HSD17B10MAPK1TSHRATM
SCHEMBL17314978 0.87 AHR (0.57) ALDH1A1HSD17B10MAPK1TSHRATM
Pyrene SCHEMBL2127931 0.85 ALDH1A1 (0.67) ALDH1A1HSD17B10TSHRATMGPR3
Carbazole SCHEMBL7171558 0.85 ALDH1A1 (0.67) ALDH1A1HSD17B10ATMGPR3HPGD
Carbazole SCHEMBL18836424 0.83 PARP1 (0.69) ALDH1A1HSD17B10ATMGPR3HPGD
SCHEMBL21302945 0.83 PARP1 (0.51) ALDH1A1HSD17B10MAPK1TSHRATM
Benzanthrone SCHEMBL1899312 0.83 PABPC1 (0.66) ALDH1A1HSD17B10MAPK1TSHRATM
SCHEMBL1326375 0.83 IMPDH2 (0.61) ALDH1A1HSD17B10MAPK1TSHRATM
SCHEMBL866840 0.83 IMPDH2 (0.61) ALDH1A1HSD17B10MAPK1TSHRATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109776542-A A kind of electroluminescent organic material and its application 北京鼎材科技有限公司 2019-05-21 CN disclosed
CN-109553620-A General formula compound and organic electroluminescence device 北京鼎材科技有限公司 2019-04-02 CN disclosed