SCHEMBL866840

SCHEMBL866840

c1ccc(-c2ccccc2-c2cccc3[nH]c4ccccc4c23)c(-c2ccccc2-c2ccccc2-c2cccc3[nH]c4ccccc4c23)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IMPDH2 P12268 1/20 0.61
IMPDH1 P20839 1/20 0.61
ALDH1A1 P00352 4/20 0.56
HSD17B10 Q99714 3/20 0.56
GPR3 P46089 1/20 0.56
GABRP O00591 4/20 0.53
GABRD O14764 4/20 0.53
GABRA1 P14867 4/20 0.53
GABRB1 P18505 4/20 0.53
GABRG2 P18507 4/20 0.53
GABRB3 P28472 4/20 0.53
GABRA5 P31644 4/20 0.53
GABRA3 P34903 4/20 0.53
GABRA2 P47869 4/20 0.53
GABRB2 P47870 4/20 0.53
GABRA4 P48169 4/20 0.53
GABRE P78334 4/20 0.53
GABRA6 Q16445 4/20 0.53
GABRG1 Q8N1C3 4/20 0.53
GABRG3 Q99928 4/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1326375 1.00 IMPDH2 (0.61) IMPDH2IMPDH1ALDH1A1HSD17B10GPR3
SCHEMBL5933739 0.98 IMPDH2 (0.63) IMPDH2IMPDH1ALDH1A1HSD17B10GPR3
SCHEMBL21407081 0.90 IMPDH2 (0.52) IMPDH2IMPDH1ALDH1A1HSD17B10GPR3
SCHEMBL20261907 0.90 IMPDH2 (0.55) IMPDH2IMPDH1ALDH1A1HSD17B10GPR3
SCHEMBL223943 0.87 IMPDH2 (0.49) IMPDH2IMPDH1ALDH1A1HSD17B10GPR3
SCHEMBL24723178 0.86 IMPDH2 (0.52) IMPDH2IMPDH1ALDH1A1HSD17B10GPR3
SCHEMBL18851614 0.86 IMPDH2 (0.52) IMPDH2IMPDH1ALDH1A1HSD17B10GPR3
SCHEMBL20934479 0.86 KIF11 (0.56) IMPDH2IMPDH1ALDH1A1HSD17B10GPR3
SCHEMBL19658965 0.86 GABRP (0.65) IMPDH2IMPDH1ALDH1A1HSD17B10GPR3
SCHEMBL1344641 0.86 IMPDH2 (0.52) IMPDH2IMPDH1ALDH1A1HSD17B10GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8940408-B2 White organic light-emitting device INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2015-01-27 US claimed
US-8319421-B2 Organic light-emitting laminate and organic electroluminescent device containing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2012-11-27 US claimed
US-20100314612-A1 WHITE ORGANIC LIGHT-EMITTING DEVICE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2010-12-16 US claimed
US-20090295278-A1 Organic light-emitting laminate and organic electroluminescent device conatiaing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2009-12-03 US claimed
US-10786683-B2 Light-emitting devices for wound healing NITTO DENKO CORPORATION (JP) 2020-09-29 US disclosed
US-9978953-B2 Substituted biphenyl compounds for use in light-emitting devices NITTO DENKO CORPORATION (JP) 2018-05-22 US disclosed
US-9917281-B2 Top-emitting white organic light-emitting diodes having improved efficiency and stability NITTO DENKO CORPORATION (JP) 2018-03-13 US disclosed
EP-2681970-B1 POROUS FILMS FOR USE IN LIGHT-EMITTING DEVICES NITTO DENKO CORP (JP) 2018-01-17 EP disclosed
US-9859517-B2 White organic light-emitting diode NITTO DENKO CORPORATION (JP) 2018-01-02 US disclosed
US-9853220-B2 Efficient organic light-emitting diodes and fabrication of the same NITTO DENKO CORPORATION (JP) 2017-12-26 US disclosed
EP-2723721-B1 POLYPHENYLENE HOST COMPOUNDS NITTO DENKO CORP (JP) 2017-08-09 EP disclosed
US-9614162-B2 Light-emitting devices comprising emissive layer NITTO DENKO CORPORATION (JP) 2017-04-04 US disclosed
US-20120179089-A1 SUBSTITUTED BIPYRIDINES FOR USE IN ORGANIC LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2012-07-12 US disclosed
WO-2012088294-A1 BENZOIMIDAZOLE DERIVATIVES FOR USE IN LIGHT - EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2012-06-28 WO disclosed
US-20120121933-A1 HYBRID COMPOSITE EMISSIVE CONSTRUCT AND LIGHT-EMITTING DEVICES USING THE SAME NITTO DENKO CORPORATION (JP) 2012-05-17 US disclosed
US-20120075278-A1 ORGANIC EL DISPLAY KABUSHIKI KAISHA TOSHIBA (JP) 2012-03-29 US disclosed
US-20110251401-A1 POLYPHENYLENE HOST COMPOUNDS NITTO DENKO CORPORATION (JP) 2011-10-13 US disclosed
US-20110140093-A1 COMPOUNDS FOR USE IN LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2011-06-16 US disclosed
US-20100314612-A1 WHITE ORGANIC LIGHT-EMITTING DEVICE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2010-12-16 US disclosed
US-20090295278-A1 Organic light-emitting laminate and organic electroluminescent device conatiaing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2009-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110251401-A1 POLYPHENYLENE HOST COMPOUNDS PPOX, PPIL1, PIN1 IMPDH2 1290/4885IMPDH1 1251/4885ALDH1A1 920/4885
US-20110140093-A1 COMPOUNDS FOR USE IN LIGHT-EMITTING DEVICES NR2E3, CYP3A4, UGT1A4 IMPDH2 2540/4885IMPDH1 2479/4885ALDH1A1 94/4885
US-20120179089-A1 SUBSTITUTED BIPYRIDINES FOR USE IN ORGANIC LIGHT-EMITTING DEVICES BRD9, PIR, BRD2 IMPDH2 1164/4885IMPDH1 1303/4885ALDH1A1 867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.