Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11035980 | 0.78 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL28228488 | 0.73 | SIGMAR1 (0.45) | — | |
| SCHEMBL28272326 | 0.73 | LMNA (0.50) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5339516 | 0.72 | LMNA (0.48) | ALDH1A1 | |
| SCHEMBL898050 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL28320590 | 0.60 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL11884863 | 0.59 | SIGMAR1 (0.35) | — | |
| SCHEMBL11820260 | 0.59 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL4565560 | 0.59 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL4093701 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110015984-A | Substituted (E)-N '-(1- phenylethylene) benzoyl hydrazine analog as histone demethylase inhibitor | 犹他大学研究基金会 | 2019-07-16 | — | — | CN | disclosed |
| CN-105555784-B | Substituted (E) -N' - (1-phenylethylene) benzoyl hydrazine analogs as histone demethylase inhibitors | 犹他大学研究基金会 | 2019-03-15 | — | — | CN | disclosed |