Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 5/20 | 0.39 |
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11035980 | 0.81 | ALDH1A1 (0.37) | MEN1KMT2A | |
| SCHEMBL3714823 | 0.81 | PLD1 (0.48) | — | |
| SCHEMBL28272326 | 0.76 | LMNA (0.50) | SIGMAR1MEN1KMT2A | |
| SCHEMBL27620685 | 0.76 | SIGMAR1 (0.45) | SIGMAR1ADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL736136 | 0.76 | SIGMAR1 (0.46) | SIGMAR1ADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL21906494 | 0.76 | SIGMAR1 (0.45) | SIGMAR1ADRB1HTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL5339516 | 0.74 | LMNA (0.48) | SIGMAR1MEN1KMT2A | |
| SCHEMBL28285202 | 0.73 | CHRM4 (0.33) | — | |
| SCHEMBL8713624 | 0.72 | SIGMAR1 (0.41) | SIGMAR1ADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL28884912 | 0.72 | SIGMAR1 (0.42) | SIGMAR1ADRB1HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341831-A | 7H- [1,2,4] triazole [3,4-b] [1,3,4] thiadiazine-phenylhydrazone type compound | 贵州医科大学 | 2018-07-31 | — | — | CN | disclosed |