Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 6/20 | 0.46 |
| ▸ | MAOA | P21397 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28286820 | 0.87 | ACHE (0.43) | ALDH1A1 | |
| SCHEMBL28652467 | 0.80 | RAB9A (0.55) | RAB9AMAOBMAOANPC1TDP1 | |
| SCHEMBL28004942 | 0.80 | POLB (0.49) | RAB9AMAOBMAOANPC1TDP1 | |
| SCHEMBL28181770 | 0.79 | KMT2A (0.49) | KDM4EALDH1A1 | |
| SCHEMBL28769996 | 0.79 | MAPT (0.58) | RAB9AMAOBNPC1FFAR1SMN1; SMN2 | |
| SCHEMBL7987753 | 0.77 | PPARA (0.48) | FFAR1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6687219 | 0.77 | MAOB (0.66) | RAB9AMAOBMAOANPC1TDP1 | |
| SCHEMBL27765570 | 0.77 | TSHR (0.43) | SMN1; SMN2 | |
| SCHEMBL8545870 | 0.76 | RAB9A (0.71) | RAB9AMAOBMAOANPC1TDP1 | |
| SCHEMBL20132198 | 0.76 | SIRT2 (0.59) | RAB9AMAOBMAOANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476699-A | Glucocorticoid receptor agonist and its immune conjugate | 艾伯维公司 | 2019-03-15 | — | — | CN | disclosed |