Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28181770 | 0.85 | KMT2A (0.49) | ALDH1A1MAPTKMT2A | |
| SCHEMBL28191611 | 0.83 | ALDH1A1 (0.47) | PPARAALDH1A1LMNAMAPTHPGD | |
| SCHEMBL7987983 | 0.81 | LMNA (0.55) | PPARAPPARGALDH1A1LMNAMAPT | |
| SCHEMBL7987926 | 0.81 | HPGD (0.63) | HPGD | |
| SCHEMBL7987925 | 0.81 | HPGD (0.63) | HPGD | |
| SCHEMBL8003930 | 0.78 | PPARA (0.49) | PPARAPPARGALDH1A1LMNAMAPT | |
| SCHEMBL28285446 | 0.77 | RAB9A (0.48) | ALDH1A1LMNASMN1; SMN2FFAR1 | |
| SCHEMBL7998395 | 0.77 | SMN1; SMN2 (0.52) | PPARAALDH1A1LMNAMAPTHPGD | |
| SCHEMBL28016853 | 0.77 | PPARA (0.54) | PPARAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27795453 | 0.77 | FAAH (0.57) | SMN1; SMN2KMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288096-B1 | ANTIDIABETIC AGENTS, HYPOTENSIVE AGENTS, AND ANTICHOLESTEROL AGENTS | ASTRAZENECA AB (SE) | 2001-09-11 | — | — | US | disclosed |
| EP-0991632-A1 | NEW THIAZOLIDINEDIONE, OXAZOLIDINEDIONE AND OXADIAZOLIDINEDIONE DERIVATIVES | Astra Aktiebolag (SE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998057941-A1 | NEW THIAZOLIDINEDIONE, OXAZOLIDINEDIONE AND OXADIAZOLIDINEDIONE DERIVATIVES | ASTRA AKTIEBOLAG (SE) | 1998-12-23 | — | — | WO | disclosed |