Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.53 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | CTSG | P08311 | 1/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.48 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13290766 | 0.83 | NFE2L2 (0.53) | PGRNFE2L2KEAP1TAS2R14HSD11B1 | |
| SCHEMBL8761688 | 0.83 | TDP1 (0.67) | TDP1SMN1; SMN2LMNAHTTL3MBTL1 | |
| SCHEMBL9116912 | 0.82 | LMNA (0.55) | TDP1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL4429067 | 0.82 | F2 (0.56) | TDP1SMN1; SMN2HTTL3MBTL1ALDH1A1 | |
| SCHEMBL14282636 | 0.81 | PGR (0.56) | PGRNFE2L2KEAP1TAS2R14HSD11B1 | |
| SCHEMBL196606 | 0.81 | TDP1 (0.70) | PGRTDP1SMN1; SMN2LMNAHTT | |
| SCHEMBL11844319 | 0.81 | LMNA (0.49) | PGRTDP1SMN1; SMN2LMNAHTT | |
| SCHEMBL22187559 | 0.81 | TSHR (0.63) | SMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL29673679 | 0.81 | TSHR (0.63) | SMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL11777522 | 0.81 | AKR1C3 (0.51) | PGRTDP1SMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109574891-A | A kind of synthetic method for the alkenyl sulfide compound that triaryl replaces | 湖南医药学院 | 2019-04-05 | — | — | CN | disclosed |