SCHEMBL4429067

SCHEMBL4429067

Cc1cccc(S(=O)(=O)Oc2ccccc2)c1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 0.56
TDP1 Q9NUW8 3/20 0.51
PPARG P37231 1/20 0.49
ALDH1A1 P00352 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
KMT2A Q03164 1/20 0.46
HTR6 P50406 1/20 0.46
HTT P42858 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
MAOB P27338 2/20 0.44
GPR17 Q13304 1/20 0.44
NPC1 O15118 1/20 0.44
MAPT P10636 1/20 0.44
RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27363990 0.94 F2 (0.51) F2TDP1PPARGALDH1A1SMN1; SMN2
SCHEMBL14872759 0.89 TDP1 (0.53) F2TDP1ALDH1A1KMT2AHTR6
SCHEMBL4127164 0.89 PPARG (0.56) F2TDP1PPARGALDH1A1SMN1; SMN2
SCHEMBL27657953 0.85 F2 (0.49) F2TDP1ALDH1A1KMT2AHTR6
SCHEMBL28286017 0.82 PGR (0.54) TDP1ALDH1A1SMN1; SMN2HTTL3MBTL1
SCHEMBL29673550 0.82 ENPP3 (0.56) KMT2AGPR17MAPT
SCHEMBL22187319 0.82 ENPP3 (0.56) KMT2AGPR17MAPT
SCHEMBL30617915 0.82 CA12 (0.57) KMT2AMAPT
SCHEMBL30617914 0.81 GPR17 (0.55) ALDH1A1SMN1; SMN2KMT2AHTTGPR17
SCHEMBL22187506 0.81 GPR17 (0.55) F2ALDH1A1SMN1; SMN2KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1928475-B1 ANTIVIRAL PHOSPHORAMIDATES OF 4'-C-AZIDO-SUBSTITUTED PRONUCLEOTIDES RIBOSCIENCE LLC (US) 2018-05-23 EP disclosed
US-7608599-B2 Antiviral phosphoramidates ROCHE PALO ALTO LLC (US) 2009-10-27 US disclosed
US-20070042988-A1 Antiviral phosphoramidates ROCHE PALO ALTO LLC 2007-02-22 US disclosed
EP-0773235-B1 Polymerization of alpha-olefins MITSUBISHI CHEM CORP (JP) 1999-05-26 EP disclosed
EP-0759445-B1 Catalyst for olefin polymerization and method for producing olefin polymers using the same MITSUBISHI CHEM CORP (JP) 1999-03-17 EP disclosed
EP-0773235-A1 Polymerization of alpha-olefins MITSUBISHI CHEMICAL CORPORATION (JP) 1997-05-14 EP disclosed
EP-0759445-A1 Catalyst for olefin polymerization and method for producing olefin polymers using the same MITSUBISHI CHEMICAL CORPORATION (JP) 1997-02-26 EP disclosed
EP-0015518-B1 METHOD FOR IMMUNOLOGICAL ANALYSIS OF TRACE COMPONENTS FUJI PHOTO FILM CO., LTD. (JP) 1983-07-20 EP disclosed
US-4337063-A PHOTOCHEMICAL METHOD FUJI PHOTO FILM CO., LTD. (JP) 1982-06-29 US disclosed
US-4331444-A Competitive immunoassay using silver halide fogging agent FUJI PHOTO FILM CO., LTD. (JP) 1982-05-25 US disclosed
EP-0015519-A1 Method for immunological analysis FUJI PHOTO FILM CO., LTD. (JP) 1980-09-17 EP disclosed
EP-0015518-A1 Method for immunological analysis of trace components FUJI PHOTO FILM CO., LTD. (JP) 1980-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070042988-A1 Antiviral phosphoramidates RPP30, RNASE1, ADORA2B F2 904/4885TDP1 1929/4885PPARG 4192/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.