SCHEMBL28286235

SCHEMBL28286235

CCC(c1ccccc1)N1C(=O)C=CC1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
OPRM1 P35372 2/20 0.41
OPRD1 P41143 2/20 0.41
OPRK1 P41145 2/20 0.41
OPRL1 P41146 2/20 0.41
HSD11B1 P28845 2/20 0.40
MGLL Q99685 5/20 0.40
GSK3A P49840 2/20 0.38
GSK3B P49841 2/20 0.38
CYP17A1 P05093 1/20 0.37
HKDC1 Q2TB90 1/20 0.37
SLC6A4 P31645 3/20 0.36
SLC6A2 P23975 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
KDM4C Q9H3R0 1/20 0.36
GMNN O75496 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
THPO P40225 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9562580 0.79 MGLL (0.46) LMNAMGLLGSK3AGSK3BMEN1
SCHEMBL12898667 0.79 ALDH1A1 (0.52) LMNAALDH1A1MAPT
SCHEMBL10973243 0.78 KMT2A (0.47) MEN1KMT2AALDH1A1MAPT
SCHEMBL28786000 0.78 MGLL (0.38) MGLLGSK3AGSK3BSLC6A4SLC6A2
SCHEMBL13878052 0.77 ALDH1A1 (0.43) OPRM1OPRD1OPRK1OPRL1HSD11B1
SCHEMBL1608836 0.75 ALDH1A1 (0.46) MGLLGSK3AGSK3BMEN1KMT2A
SCHEMBL8871482 0.75 ALDH1A1 (0.41) LMNAKMT2AALDH1A1NPSR1
SCHEMBL8871478 0.75 ALDH1A1 (0.41) LMNAKMT2AALDH1A1NPSR1
SCHEMBL11082175 0.74 MEN1 (0.55) LMNAOPRM1OPRD1OPRK1OPRL1
SCHEMBL3817361 0.74 ALDH1A1 (0.50) LMNAMGLLMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110527019-B Bismaleimide resin microsphere and preparation method thereof 北京化工大学 2021-04-02 CN claimed
CN-113880986-A High-temperature high-pressure hydrolysis-resistant bismaleimide resin composition and preparation method and application thereof 中国石油化工股份有限公司 2022-01-04 CN disclosed
CN-110527019-B Bismaleimide resin microsphere and preparation method thereof 北京化工大学 2021-04-02 CN disclosed
CN-109453167-A Maleimide class compound is preparing the application in Li Shiman protozoon insecticide 浙江工业大学 2019-03-12 CN disclosed