Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.53 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | PEPD | P12955 | 2/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.43 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSH | P09668 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21536111 | 1.00 | CTSK (0.53) | CTSKCTSSKLK5PEPDFKBP1A | |
| SCHEMBL19744673 | 0.90 | CTSS (0.56) | CTSKCTSSPEPDACELMNA | |
| SCHEMBL19744672 | 0.90 | CTSS (0.56) | CTSKCTSSPEPDACELMNA | |
| SCHEMBL28186217 | 0.86 | KLK5 (0.52) | KLK5PEPDFKBP1AACELMNA | |
| SCHEMBL30193081 | 0.86 | KLK5 (0.52) | KLK5PEPDFKBP1AACEXPNPEP1 | |
| SCHEMBL21506053 | 0.84 | CTSS (0.50) | CTSKCTSSKLK5AAK1HDAC4 | |
| SCHEMBL8365033 | 0.84 | CTSL (0.54) | CTSKCTSSKLK5FKBP1AACE | |
| SCHEMBL7144197 | 0.84 | CTSL (0.54) | CTSKCTSSKLK5FKBP1AACE | |
| SCHEMBL18630366 | 0.83 | KLK5 (0.49) | KLK5PEPDFKBP1AACEXPNPEP1 | |
| SCHEMBL21119405 | 0.83 | CTSS (0.47) | CTSKCTSSKLK5AAK1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563033-B | Aliphatic prolinamide derivatives | 奥瑞恩眼科有限责任公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-109563033-A | Aliphatic Prolinamide derivatives | 奥瑞恩眼科有限责任公司 | 2019-04-02 | — | — | CN | disclosed |