Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
| ▸ | PEPD | P12955 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.41 |
| ▸ | CMA1 | P23946 | 5/20 | 0.40 |
| ▸ | CTRC | Q99895 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8254962 | 0.88 | CTSK (0.50) | KLK5PEPDACEXPNPEP1FKBP1A | |
| SCHEMBL28186217 | 0.87 | KLK5 (0.52) | KLK5PEPDACEXPNPEP1FKBP1A | |
| SCHEMBL30193081 | 0.87 | KLK5 (0.52) | KLK5PEPDACEXPNPEP1FKBP1A | |
| SCHEMBL10144067 | 0.87 | TSHR (0.52) | KLK5PEPDACEXPNPEP1FKBP1A | |
| SCHEMBL28286258 | 0.83 | CTSK (0.53) | KLK5PEPDACEXPNPEP1FKBP1A | |
| SCHEMBL21536111 | 0.83 | CTSK (0.53) | KLK5PEPDACEXPNPEP1FKBP1A | |
| SCHEMBL8005012 | 0.83 | ITGB3 (0.45) | KLK5PEPDACEXPNPEP1FKBP1A | |
| SCHEMBL21409190 | 0.83 | KLK5 (0.62) | KLK5ACEF2PRSS1CMA1 | |
| SCHEMBL21409191 | 0.83 | KLK5 (0.62) | KLK5ACEF2PRSS1CMA1 | |
| SCHEMBL21409192 | 0.83 | KLK5 (0.62) | KLK5ACEF2PRSS1CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170073370-A1 | BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS, INC. | 2017-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170073370-A1 | BROAD SPECTRUM ANTIBIOTICS | SPAST, NPEPPS, SPOUT1 | KLK5 1116/4885PEPD 7/4885ACE 153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.