Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | LGMN | Q99538 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20631 | 0.89 | MAPT (0.61) | MAPTALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL19221733 | 0.88 | MAPT (0.57) | MAPTALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL20631313 | 0.87 | LMNA (0.61) | MAPTALDH1A1KDM4ESMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL16209945 | 0.87 | MAPT (0.65) | MAPTALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL14320289 | 0.83 | PIK3R1 (0.59) | MAPTALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL4386393 | 0.82 | MAPT (0.64) | MAPTALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL28286793 | 0.79 | AKR1C3 (0.54) | MAPTALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL4689823 | 0.79 | ALDH1A1 (0.52) | MAPTALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL19648927 | 0.79 | MAPT (0.50) | MAPTALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL30706470 | 0.79 | ADRA2C (0.53) | MAPTALDH1A1KDM4ESMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014285-B1 | NPYY5 antagonists | SHIONOGI & CO (JP) | 2010-05-05 | — | — | EP | disclosed |