Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 8/20 | 0.54 |
| ▸ | RXRG | P48443 | 8/20 | 0.54 |
| ▸ | RXRB | P28702 | 7/20 | 0.54 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.54 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.54 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.54 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.54 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.54 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL267205 | 0.86 | RXRA (0.68) | RXRARXRGRXRBPSEN1PSEN2 | |
| SCHEMBL202439 | 0.86 | CA2 (0.56) | RXRARXRBNR1H4CYP3A4 | |
| SCHEMBL28287472 | 0.86 | MEN1 (0.51) | RXRARXRGRXRBPSEN1PSEN2 | |
| SCHEMBL28287531 | 0.84 | KCNH2 (0.51) | KCNH2CYP2C9CYP3A4CYP2D6CYP2C19 | |
| Water SCHEMBL28015733 | 0.84 | RXRA (0.66) | RXRARXRGRXRBPSEN1PSEN2 | |
| Hydrochloric Acid SCHEMBL2528774 | 0.84 | RXRA (0.66) | RXRARXRGRXRBPSEN1PSEN2 | |
| Hydrochloric Acid SCHEMBL5113831 | 0.84 | CA2 (0.54) | RXRARXRBNR1H4CYP3A4 | |
| SCHEMBL5449110 | 0.81 | RXRA (0.51) | RXRARXRGRXRBPSEN1PSEN2 | |
| SCHEMBL2272003 | 0.81 | RXRA (0.77) | RXRARXRGRXRBPSEN1PSEN2 | |
| SCHEMBL11031787 | 0.80 | NR1H4 (0.49) | RXRARXRGRXRBNR1H4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641844-A | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2019-04-16 | — | — | CN | disclosed |